How does HPMC work?

Hydroxypropyl methylcellulose (HPMC) is a semi-synthetic cellulose ether polymer. Its unique physical and chemical properties, including water solubility, film-forming properties, thickening, and gelling properties, make it an important player in the pharmaceutical, food, and industrial sectors.

In the pharmaceutical sector, HPMC is widely used in solid dosage forms. As a coating material, the thin film it forms blocks moisture, light, and oxygen, enhancing drug stability. In controlled-release formulations, HPMC swells in water to form a gel barrier, regulating drug release rate through diffusion and dissolution mechanisms, achieving long-term sustained release. Furthermore, it acts as a binder to improve tablet mechanical strength and formability.

In the food industry, HPMC is used as an additive to thicken, emulsify, and stabilize systems. Its aqueous solution exhibits excellent viscosity and colloidal properties, improving the texture and mouthfeel of foods such as sauces and ice cream. It can also replace fat in certain products to reduce calories.

In construction and industrial applications, HPMC is primarily used as a water-retention agent and thickener in cement- and gypsum-based materials, improving workability and sag resistance. In coatings, it acts as a film-forming agent and rheology modifier, ensuring uniform and smooth coatings. It is also used in ceramic and plastic processing to improve lubrication and mold release properties.

HPMC is derived from natural cellulose and is biodegradable, environmentally friendly, and in line with green and sustainable development requirements. Its versatility and favorable ecological profile give it broad application potential in a wide range of current and future technological fields.